P-003 ASSESSMENT OF UROSTOMY PARASTOMAL HERNIATION FORCES

Abstract Introduction Approximately 10,000 patients undergo cystectomy with ileal conduit diversion annually in the USA, of which ∼ 50% will subsequently develop a parastomal hernia (PSH) at 2 years. Due to knowledge gap between urostomy surgical factors and abdominal wall forces, we developed silicone ex-vivo human cadaver fascia-based model for study. Our objective was measure relationship incision size/type/material axial tension force (ATF) as surrogate herniation force. Methods Using incisions (linear, cruciate, circular) ranging 1 3 cm (0.5cm increments) clamped 3″x3″x0.020″ or cadaveric sheets, dynamometer hooked Foley catheter drainage aperture pulled using motorized positioning system 20 millimeters/minute. Balloons were hydrated 125% dimension. Upward ATF recorded until balloon repeated up N=5 membranes/size. As limited fascia available, single size used. Results Controlling size, linear highest. With an average 3cm 18.58, 8.48, 2.36 Newtons circular respectively), greater than cruciate (p<0.0001), (p=0.0039). This true vs (p=0.0001) (p=0.0024). Conclusion study suggests type/size have predictable influences on herniation. En-bloc studies are underway assess these more clinically optimized models. If confirmed, data can help standardize creation, reducing PSH risk.